18521 Wayne Rd: $5.25M Majestic Lakefront Estate with Resort-Style Luxury in Odessa

Date of Publishing: June 22, 2025

A Landmark Odessa Estate Blending Privacy, Scale, and Architectural Excellence

Set within the gated enclave of Keystone Reserve on 4.75 manicured acres, 18521 Wayne Rd stands out as one of the finest home in Odessa for sale today. Newly listed at $5.3 million, this majestic property spans 9,922 square feet of living space and nearly 15,000 square feet under roof, combining classical architecture with cutting-edge technology.

Lakefront luxury estate at 18521 Wayne Rd in Odessa FL featuring a resort-style saltwater pool, grand circular driveway, and manicured 4.75-acre grounds

Built in 2013, this estate was acquired in 2010 for $240,000 and is now available for the first time. Its transformation into a luxury showpiece mirrors the evolution of high-end Odessa real estate, now highly coveted for privacy, space, and proximity to Tampa’s lifestyle scene. “From the gated drive to the interior finishes, every inch of this home was designed to impress,” said Austin Marks of Compass Florida, in an interview with Luxury Houses Magazine. “There’s nothing like it currently on the Odessa market.”

Thoughtfully Designed Interiors for Modern Living

Upon arrival, a circular driveway anchored by a stone fountain sets the stage. The grand foyer features marble flooring, a spiral staircase, and soaring ceilings. French doors open onto expansive covered patios, providing seamless indoor-outdoor transitions throughout the Odessa home for sale.

The chef’s kitchen is a standout, boasting Viking double ovens, a Miele coffee station, double microwaves, dual dishwashers, two deep sinks, a pot filler, and under-cabinet lighting. The massive center island and hidden walk-in pantry – with additional refrigeration – elevate both function and style. Adjacent spaces include a breakfast nook, formal dining room, and wine cellar. “The kitchen truly anchors this home,” Marks added. “It’s designed for entertaining, but also meets every expectation for daily luxury.”

SEE MORE: Spectacular $26.5 Million Smart Estate in Boca Raton Offers Turnkey Waterfront Living and Resort Elegance

Entertainment Wing with Custom Theater and More

The left wing of the Odessa real estate is dedicated to leisure and wellness. A custom movie theater, fully stocked bar, pool table area, and bonus rooms for a home gym and art studio offer flexible lifestyle choices. Sliding glass doors lead to the 1,169-square-foot lanai, outfitted with an outdoor kitchen, fireplace, and floating TV.

A private guest suite with en-suite bath – ideal as a maid’s or in-law quarters – adds practical sophistication. The adjacent laundry room includes double washers and dryers, custom cabinetry, and ample storage for a large household.

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Grand Owner’s Suite and Private Executive Wing

On the opposite wing lies the executive office with a private loggia, a formal living room with fireplace, and the primary suite. Here, luxury takes center stage with a wet bar, tray ceilings, private lanai access, dual walk-in closets (one with an island), and a spa-inspired bathroom complete with jacuzzi tub, rain shower, and his-and-hers vanities.

A representative from Luxury Houses reached out to the homeowner for insights into the estate’s design vision. While they declined to be quoted, it’s clear that a deep level of care and investment has been made into every architectural decision.

Accessible via elevator or two grand staircases, the upstairs level features four en-suite bedrooms, each with walk-in closets. A cozy loft nook includes a built-in desk and reading area, while a large bonus room with wet bar, microwave, and walk-in closet opens onto a 1,319-square-foot balcony with panoramic lake views. “The second floor adds another dimension of luxury, ideal for multigenerational living or long-term guests,” said Marks when speaking to Luxury Houses Magazine.

SEE MORE: Majestic Kissimmee Estate Blends Mediterranean Elegance with Resort-Style Living for $5.9 Million

Outdoor Oasis with Resort-Style Amenities

The backyard at 18521 Wayne Rd is nothing short of a private resort. A 60,000-gallon saltwater pool features an integrated waterslide, rock waterfall, and 12-person spa, all surrounded by tropical landscaping and a charming footbridge. A private lakefront dock offers boating and fishing access, and an outdoor shower completes the experience.

Other exterior features include a tennis and basketball court, mature fruit trees, a perennial garden, firepit, and lighting throughout the grounds. The 8-car garage with tandem bays and a utility garage supports vehicle collectors and hobbyists alike.

Premium Infrastructure and Odessa Real Estate Context

This Odessa home for sale comes equipped with a 48kW whole-house generator, five zoned HVAC systems, three new water heaters, a 1,000-gallon propane tank, Control4 smart home systems, and zoned thermostats in every bedroom. The property is on well water and septic, with a $150/month HOA fee and 2024 taxes of $41,914.

Located within Odessa’s premier community, Keystone Reserve, this home offers quick access to major highways, downtown Tampa (30 minutes), Tampa International Airport, and top-rated schools. Upscale dining, shopping, and equestrian trails are just minutes away, making it one of the most well-positioned Odessa real estate assets on the market.

Final Word from Luxury Houses Magazine

18521 Wayne Rd is more than just square footage – it’s a lifestyle blueprint for those seeking space, privacy, and long-term value. From smart-home integration to luxurious outdoor living, it ranks among the finest luxury homes in Odessa for sale today.